Home drugs Hyper-CVAD


This page contains brief information about the drug combination called hyper-CVAD. The drugs in the combination are listed, and links to individual drug summaries are included.

Drugs in the hyper-CVAD combination:
C = Cyclophosphamide
V = Vincristine Sulfate
A = Doxorubicin Hydrochloride (Adriamycin)
D = Dexamethasone

Methotrexate and Cytarabine are also given as part of this combination.

Chemotherapy is often given as a combination of drugs. Combinations usually work better than single drugs because different drugs kill cancer cells in different ways.

Each of the drugs in this combination is approved by the Food and Drug Administration (FDA) to treat cancer or conditions related to cancer.

Use in Cancer

Hyper-CVAD with methotrexate and cytarabine is used to treat:

  • Acute lymphoblastic leukemia (certain types).
  • Non-Hodgkin lymphoma (certain types).

Hyper-CVAD is given as hyperfractionated therapy, in which the total daily dose is divided into smaller doses and given more than once a day.

This combination may also be used with other drugs or treatments or to treat other types of cancer.

More About Hyper-CVAD

Definition from the TCH Drug Dictionary – Detailed scientific definition and other names for this drug.